Pomegranate Extract—Supporting Healthy Blood Pressure

BY DIANA ALLEN, MS, CNS

Pomegranate Extract

High blood pressure is one of the most widespread health challenges across the developed world.

In the United States, nearly forty-five percent of adults are affected by hypertension—defined as blood pressure readings at or above 140/90 mmHg.

Simple, natural approaches, such as incorporating antioxidants like pomegranate extract, can gently support cardiovascular health.

Even a modest reduction in blood pressure can yield significant health benefits. Research shows that a drop of just 5 mmHg in either systolic or diastolic pressure may reduce the risk of heart disease and stroke by up to twenty percent.

In many if not most cases, chronically elevated blood pressure is a result of modifiable lifestyle factors—meaning it can often be improved, and even reversed, through changes in daily habits.

Regular walking, stress management, and anti-inflammatory nutrition form the cornerstone of a natural strategy to support healthy blood pressure levels.

The Role of Nutrition—and the Power of Pomegranate Extract

Among the most promising nutrition-based approaches is pomegranate, a fruit long celebrated for its antioxidant power.

Pomegranate is rich in polyphenols—including punicalagins, tannins, and anthocyanins—that have been shown to reduce vascular inflammation, support healthy endothelial function, and promote vasodilation—the widening of blood vessels that helps ease blood flow.

A randomized, double-blind, placebo-controlled trial published in the Journal of Nutritional Science explored the effects of pomegranate extract (PE) on blood pressure and body composition.

The eight-week study involved fifty-five normotensive adults, none of whom had underlying heart, kidney, or metabolic conditions.

Participants were divided into two groups.

One group received a daily capsule of Pomanox®—a standardized whole pomegranate extract developed in Europe using a proprietary water-based process to preserve its active compounds. The other group received a placebo.

Both groups were instructed to take their capsules with water after a meal and were not asked to modify their diets or exercise routines.

Researchers tracked each participant’s blood pressure, body composition (body fat percentage, waist circumference, and lean mass), and biomarkers of oxidative stress over the course of the study—at baseline, week four, and week eight.

Measurable Improvements

By the end of the study, the Pomanox® group showed a statistically significant average decrease of 2.8 mmHg in diastolic blood pressure—the lower number in a blood pressure reading, which reflects the pressure in the arteries between heartbeats.

Systolic pressure—the upper number, which measures pressure during a heartbeat—also decreased by an average of 2.37 mmHg. No change was observed in the placebo group.

What makes these findings particularly compelling is that they occurred without any changes to diet or physical activity, suggesting that pomegranate extract alone may support healthier cardiovascular function.

Further research supports these results. A recent study involving twenty-four healthy participants found that those supplementing with Pomanox® experienced decreased body fat, increased lean mass, and significant reductions in both systolic and diastolic blood pressure, compared to control.

Study authors concluded, “The PE extract possesses anti-hypertensive, anti-atherogenic and cardioprotective effects and highlights the beneficial effects of PE on blood pressure, arterial stiffness, and body composition, all of which are potential risk factors in the development of cardiovascular disease.”

While long-term wellness requires a commitment to healthy habits, pomegranate extract offers a simple, natural way to support blood pressure and vascular health.

As part of a daily wellness regimen, it has been shown to help improve circulation, reduce inflammation, and protect the heart—one small habit with meaningful impact.

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Diana Allen, MS, CNS, is a clinical nutritionist in private practice and the Product Development Manager at Moss Nutrition. She is a regular contributor to Well Being Journal and the author of numerous health articles and three booklets—Chia Seed, Kombucha, and Natural & Healthy Sweeteners (Woodland Publishing). Diana can be reached at diana@mossnutrition.com or through her website www.eat2evolve.net.

Well Being Journal adapted the above excerpt from Moss Nutrition Digest (#43) “Improving Blood Flow with Pomegranate” by Diana Allen, MS, CNS.

REFERENCES

Stockton A, Farhat G, et al. “Effect of pomegranate extract on blood pressure and anthropometry in adults: a double-blind placebo-controlled randomized clinical trial.” J Nutr Sci. 2017 Aug 9:6:e39.

Vilahur G, Padro T, et al. “Polyphenol-enriched diet prevents coronary endothelial dysfunction by activating the Akt/eNOS pathway.” Rev Esp Cardiol (Engl Ed). 2015 Mar;68(3):216-25.

Al-Dujaili EAS, Casey C, et al. “Antioxidant Properties and Beneficial Cardiovascular Effects of a Natural Extract of Pomegranate in Healthy Volunteers: A Randomized Preliminary Single-Blind Controlled Study.” Antioxidants (Basel). 2022 Oct 28;11(11):2124.

Eric T Trexler, Abbie E Smith-Ryan, et al. “The effects of pomegranate extract on blood flow and running time to exhaustion,” Appl Physiol Nutr Metab. 2014 May 16;39(9):1038–1042.

Achraf Ammar, Stephen J Bailey, et al. “Effects of pomegranate supplementation on exercise performance and post-exercise recovery in healthy adults: a systematic review,” Br J Nutr. 2018 Dec;120(11):1201-1216.

Elizabeth C Lefferts, Joseph M Saavedra, et al. “Increasing Lifestyle Walking by 3000 Steps per Day Reduces Blood Pressure in Sedentary Older Adults with Hypertension: Results from an e-Health Pilot Study,” J Cardiovasc Dev Dis. 2023 Jul 27;10(8):317.

Anna Zarra Aldrich (2023) “Increasing steps by 3,000 per day can lower blood pressure in older adults,” UConn Today. Available at: https://today.uconn. edu/2023/09/increasing-steps-by-3000per-day-can-lower-blood-pressure-inolder-adults/.

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